UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C.  20549
   
   
SCHEDULE 13G*/
(Rule 13d-102)
   
   
Spruce Biosciences, Inc.
(Name of Issuer)
   
Common stock, par value $0.0001 per share
(Title of Class of Securities)
   

85209E109

(CUSIP Number)
   

October 14, 2020

Date of Event Which Requires Filing of the Statement  
     

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

 

¨ Rule 13d-1(b)
x Rule 13d-1(c)
¨ Rule 13d-1(d)

 

 

*/ The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

 

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

 

 

CUSIP No. 85209E109 13G Page 2 of 14 Pages

 

1.

NAME OF REPORTING PERSON

 

Citadel Advisors LLC

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)       ¨

(b)       ¨

3. SEC USE ONLY
4.

CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

0

6.

SHARED VOTING POWER

1,701,787 shares

7.

SOLE DISPOSITIVE POWER

0

8.

SHARED DISPOSITIVE POWER

See Row 6 above

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

See Row 6 above

10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES  ¨
11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

7.3%1

12.

TYPE OF REPORTING PERSON

IA; OO; HC

 

 

1The percentages reported in this Schedule 13G are based upon 23,163,593 shares of common stock outstanding after the underwriters’ exercise of their option to purchase additional shares (according to the issuer’s prospectus as filed with the Securities and Exchange Commission on October 9, 2020). Except as described in the preceding sentence, all share numbers for the holdings of the reporting persons reported in this Schedule 13G are as of the opening of the market on October 26, 2020.

 

 

 

 

CUSIP No. 85209E109 13G Page 3 of 14 Pages

 

1.

NAME OF REPORTING PERSON

 

Citadel Advisors Holdings LP

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)       ¨

(b)       ¨

3. SEC USE ONLY
4.

CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

0

6.

SHARED VOTING POWER

1,701,787 shares

7.

SOLE DISPOSITIVE POWER

0

8.

SHARED DISPOSITIVE POWER

See Row 6 above

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

See Row 6 above

10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES  ¨
11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

7.3%

12.

TYPE OF REPORTING PERSON

PN; HC

 

 

 

 

CUSIP No. 85209E109 13G Page 4 of 14 Pages

 

1.

NAME OF REPORTING PERSON

 

Citadel GP LLC

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)       ¨

(b)       ¨

3. SEC USE ONLY
4.

CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

0

6.

SHARED VOTING POWER

1,701,787 shares

7.

SOLE DISPOSITIVE POWER

0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

See Row 6 above.

10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES  ¨
11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

7.3%

12.

TYPE OF REPORTING PERSON

OO; HC

 

 

 

 

CUSIP No. 85209E109 13G Page 5 of 14 Pages

 

1.

NAME OF REPORTING PERSON

 

Citadel Securities LLC

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)       ¨

(b)       ¨

3. SEC USE ONLY
4.

CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

0

6.

SHARED VOTING POWER

0 shares

7.

SOLE DISPOSITIVE POWER

0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

See Row 6 above.

10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES  ¨
11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

0%

12.

TYPE OF REPORTING PERSON

BD, OO

 

 

 

 

CUSIP No. 85209E109 13G Page 6 of 14 Pages

 

1.

NAME OF REPORTING PERSON

 

CALC IV LP

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)       ¨

(b)       ¨

3. SEC USE ONLY
4.

CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

0

6.

SHARED VOTING POWER

0 shares

7.

SOLE DISPOSITIVE POWER

0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

See Row 6 above.

10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES  ¨
11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

0%

12.

TYPE OF REPORTING PERSON

PN; HC

 

 

 

 

CUSIP No. 85209E109 13G Page 7 of 14 Pages

 

1.

NAME OF REPORTING PERSON

 

Citadel Securities GP LLC

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)       ¨

(b)       ¨

3. SEC USE ONLY
4.

CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

0

6.

SHARED VOTING POWER

0 shares

7.

SOLE DISPOSITIVE POWER

0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

See Row 6 above.

10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES  ¨
11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

0%

12.

TYPE OF REPORTING PERSON

OO; HC

 

 

 

 

CUSIP No. 85209E109 13G Page 8 of 14 Pages

 

1.

NAME OF REPORTING PERSON

 

Kenneth Griffin

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)       ¨

(b)       ¨

3. SEC USE ONLY
4.

CITIZENSHIP OR PLACE OF ORGANIZATION

U.S. Citizen

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

0

6.

SHARED VOTING POWER

1,701,787 shares

7.

SOLE DISPOSITIVE POWER

0

8.

SHARED DISPOSITIVE POWER

See Row 6 above

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

See Row 6 above

10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES  ¨
11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

7.3%

12.

TYPE OF REPORTING PERSON

IN; HC

 

 

 

 

CUSIP No. 85209E109 13G Page 9 of 14 Pages

 

Item 1(a)Name of Issuer

Spruce Biosciences, Inc.

 

Item 1(b)Address of Issuer’s Principal Executive Offices
2001 Junipero Serra Boulevard, Suite 640, Daly City, California 94014

 

Item 2(a)Name of Person Filing
This Schedule 13G is being jointly filed by Citadel Advisors LLC (“Citadel Advisors”), Citadel Advisors Holdings LP (“CAH”), Citadel GP LLC (“CGP”), Citadel Securities LLC (“Citadel Securities”), CALC IV LP (“CALC4”), Citadel Securities GP LLC (“CSGP”) and Mr. Kenneth Griffin (collectively with Citadel Advisors, CAH, CGP, Citadel Securities, CALC4 and CSGP, the “Reporting Persons”) with respect to shares of common stock of the above-named issuer owned by Citadel Multi-Strategy Equities Master Fund Ltd., a Cayman Islands limited company (“CM”).

 

Citadel Advisors is the portfolio manager for CM. CAH is the sole member of Citadel Advisors. CGP is the general partner of CAH. CALC4 is the non-member manager of Citadel Securities. CSGP is the general partner of CALC4. Mr. Griffin is the President and Chief Executive Officer of CGP, and owns a controlling interest in CGP and CSGP.

 

The filing of this statement shall not be construed as an admission that any of the Reporting Persons is the beneficial owner of any securities covered by the statement other than the securities actually owned by such person (if any).

 

Item 2(b)Address of Principal Business Office
The address of the principal business office of each of the Reporting Persons is 131 S. Dearborn Street, 32nd Floor, Chicago, Illinois 60603.

 

Item 2(c)Citizenship
Each of Citadel Advisors, CGP, Citadel Securities and CSGP is organized as a limited liability company under the laws of the State of Delaware. Each of CALC4 and CAH is organized as a limited partnership under the laws of the State of Delaware. Mr. Griffin is a U.S. citizen.

 

Item 2(d)Title of Class of Securities
Common stock, par value $0.0001 per share

 

Item 2(e)CUSIP Number
85209E109

 

 

 

 

CUSIP No. 85209E109 13G Page 10 of 14 Pages

 

Item 3If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b) or (c), check whether the person filing is a:

 

(a)¨ Broker or dealer registered under Section 15 of the Exchange Act;

 

(b)¨ Bank as defined in Section 3(a)(6) of the Exchange Act;

 

(c)¨ Insurance company as defined in Section 3(a)(19) of the Exchange Act;

 

(d)¨ Investment company registered under Section 8 of the Investment Company Act;

 

(e)¨ An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);

 

(f)¨ An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F);

 

(g)¨ A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G);

 

(h)¨ A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act;

 

(i)¨ A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act;

 

(j)¨ A non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J);

 

(k)¨ Group, in accordance with Rule 13d-1(b)(1)(ii)(K).

 

If filing as a non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J), please specify the type of institution: ____________.

 

 

 

 

CUSIP No. 85209E109 13G Page 11 of 14 Pages

 

Item 4Ownership

 

A.Citadel Advisors LLC, Citadel Advisors Holdings LP and Citadel GP LLC

 

(a)Each of Citadel Advisors LLC, Citadel Advisors Holdings LP and Citadel GP LLC may be deemed to beneficially own 1,701,787 shares of common stock.

 

(b)The number of shares each of Citadel Advisors LLC, Citadel Advisors Holdings LP and Citadel GP LLC may be deemed to beneficially own constitutes approximately 7.3% of the common stock outstanding.

 

(c)Number of shares as to which such person has:

 

(i)sole power to vote or to direct the vote: 0

 

(ii)shared power to vote or to direct the vote: 1,701,787

 

(iii)sole power to dispose or to direct the disposition of: 0

 

(iv)shared power to dispose or to direct the disposition of: 1,701,787

 

B.Citadel Securities LLC, CALC IV LP and Citadel Securities GP LLC

 

(a)Each of CALC IV LP and Citadel Securities GP LLC may be deemed to beneficially own 0 shares of common stock.

 

(b)The number of shares that each of Citadel Securities LLC, CALC IV LP and Citadel Securities GP LLC may be deemed to beneficially own constitutes 0% of the common stock outstanding.

 

(c)Number of shares as to which such person has:

 

(i)sole power to vote or to direct the vote: 0

 

(ii)shared power to vote or to direct the vote: 0

 

(iii)sole power to dispose or to direct the disposition of: 0

 

(iv)shared power to dispose or to direct the disposition of: 0

 

C.Kenneth Griffin

 

(a)Mr. Griffin may be deemed to beneficially own 1,701,787 shares of common stock.

 

(b)The number of shares that Mr. Griffin may be deemed to beneficially own constitutes approximately 7.3% of the common stock outstanding.

 

 

 

 

CUSIP No. 85209E109 13G Page 12 of 14 Pages

 

(c)Number of shares as to which such person has:

 

(i)sole power to vote or to direct the vote: 0

 

(ii)shared power to vote or to direct the vote: 1,701,787

 

(iii)sole power to dispose or to direct the disposition of: 0

 

(iv)shared power to dispose or to direct the disposition of: 1,701,787

 

 

 

 

CUSIP No. 85209E109 13G Page 13 of 14 Pages

 

Item 5Ownership of Five Percent or Less of a Class
If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following ¨.

 

Item 6Ownership of More than Five Percent on Behalf of Another Person

Not Applicable

 

Item 7Identification and Classification of the Subsidiary which Acquired the Security Being Reported on by the Parent Holding Company

See Item 2 above

 

Item 8Identification and Classification of Members of the Group

Not Applicable

 

Item 9Notice of Dissolution of Group

Not Applicable

 

Item 10Certification
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

 

 

 

 

CUSIP No. 85209E109 13G Page 14 of 14 Pages

 

After reasonable inquiry and to the best of its knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct.

 

Dated this 26th day of October, 2020.

 

CITADEL SECURITIES LLC   CITADEL ADVISORS LLC    
     
By: /s/ Guy Miller   By: /s/ Noah Goldberg
  Guy Miller, Authorized Signatory     Noah Goldberg, Authorized Signatory
         
CALC IV LP   CITADEL ADVISORS HOLDINGS LP
     
By: /s/ Guy Miller   By: /s/ Noah Goldberg
  Guy Miller, Authorized Signatory     Noah Goldberg, Authorized Signatory
         
CITADEL SECURITIES GP LLC   CITADEL GP LLC
     
By: /s/ Guy Miller   By: /s/ Noah Goldberg
  Guy Miller, Authorized Signatory     Noah Goldberg, Authorized Signatory
         
      KENNETH GRIFFIN
       
      By: /s/ Noah Goldberg
        Noah Goldberg, attorney-in-fact*

 

 

*Noah Goldberg is signing on behalf of Kenneth Griffin as attorney-in-fact pursuant to a power of attorney previously filed with the Securities and Exchange Commission, and hereby incorporated by reference herein. The power of attorney was filed as an attachment to a filing by Citadel Advisors LLC on Schedule 13G for Zentalis Pharmaceuticals Inc. on April 9, 2020.

 

 

 

 

EXHIBIT 99.1

 

JOINT FILING AGREEMENT

 

The undersigned hereby agree that the Statement on Schedule 13G filed herewith (and any amendments thereto), relating to the common stock of Spruce Biosciences, Inc., a Delaware corporation, is being filed jointly with the Securities and Exchange Commission pursuant to Rule 13d-1(c) under the Securities Exchange Act of 1934, as amended, on behalf of each of the undersigned.

 

This Agreement may be executed in counterparts and each of such counterparts taken together shall constitute one and the same instrument.

 

Dated this 26th day of October, 2020.

 

CITADEL SECURITIES LLC   CITADEL ADVISORS LLC    
     
By: /s/ Guy Miller   By: /s/ Noah Goldberg
  Guy Miller, Authorized Signatory     Noah Goldberg, Authorized Signatory
         
CALC IV LP   CITADEL ADVISORS HOLDINGS LP
     
By: /s/ Guy Miller   By: /s/ Noah Goldberg
  Guy Miller, Authorized Signatory     Noah Goldberg, Authorized Signatory
         
CITADEL SECURITIES GP LLC   CITADEL GP LLC
     
By: /s/ Guy Miller   By: /s/ Noah Goldberg
  Guy Miller, Authorized Signatory     Noah Goldberg, Authorized Signatory
         
      KENNETH GRIFFIN
       
      By: /s/ Noah Goldberg
        Noah Goldberg, attorney-in-fact*

 

 

*Noah Goldberg is signing on behalf of Kenneth Griffin as attorney-in-fact pursuant to a power of attorney previously filed with the Securities and Exchange Commission, and hereby incorporated by reference herein. The power of attorney was filed as an attachment to a filing by Citadel Advisors LLC on Schedule 13G for Zentalis Pharmaceuticals Inc. on April 9, 2020.